Sydenham chorea (SC), or rheumatic chorea, is one of the major clinical manifestations of acute rheumatic fever (ARF) and is the most common form of acquired chorea in childhood. It is a movement disorder characterized by chorea (involuntary brief, random and irregular movements of the limbs and face), emotional lability, and hypotonia. Sydenham chorea usually develops in children between the ages of 5-15, usually following streptococcal infection. One distinct finding of Sydenham chorea is that it is almost never seen in children below 5 years of age. Rarely, the disorder has been reported in adults. Sydenham chorea affects individuals of .
Sydenham's chorea, also known as chorea minor and historically referred to as St Vitus' dance, is a disorder characterized by rapid, uncoordinated jerking movements primarily affecting the face, hands and feet. Sydenham's chorea results from childhood infection with Group A beta-haemolytic Streptococcus and is reported to occur in 20–30% of people with acute rheumatic fever.Specialty: Neurology. UpToDate, electronic clinical resource tool for physicians and patients that provides information on Adult Primary Care and Internal Medicine, Allergy and Immunology, Cardiovascular Medicine, Emergency Medicine, Endocrinology and Diabetes, Family Medicine, Gastroenterology and Hepatology, Hematology, Infectious Diseases, Nephrology and.
Physical. Because Huntington disease (HD) is the most clearly defined choreatic disease, its physical findings are described here. HD is caused by an expansion repeat (CAG) mutation in the IT15 ("interesting transcript 15") gene (which codes for the protein called huntingtin) on chromosome 4. Initial signs of chorea generally are flickers in the fingers and ticlike grimaces of the face.